Amoebiasis; Causes, Symptoms, Diagnosis, Treatment

Amoebiasis

Amoebiasis also is known amoebic dysentery, is an infection caused by any of the amoebas of the Entamoeba group & parasitic infection of the intestines caused by the protozoan Entamoeba histolytica, or E. histolytica. Symptoms are most common during infection by Entamoeba histolytica. Amoebiasis can be present with no, mild, or severe symptoms. Symptoms may include abdominal pain, diarrhea, or bloody diarrhea. Complications can include inflammation of the colon with tissue death or perforation, which may result in peritonitis. People affected may develop anemia due Read More …

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Frovatriptan; Uses, Dosage, Side Effects, Interactions

Frovatriptan

Frovatriptan is a triptan drug Serotonin-1b and Serotonin-1d Receptor Agonist for the treatment of migraine headaches, in particular, those associated with menstruation. The product is licensed to Endo Pharmaceuticals in North America and Menarini in Europe. Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head. It is available as 2. 5 mg tablets. Frovatriptan is a triptan drug Read More …

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Eletriptan; Uses, Dosage, Side Effects, Interactions

Eletriptan

Eletriptan is a Serotonin-1b and Serotonin-1d Receptor Agonist. The mechanism of action of eletriptan is as a Serotonin 1b Receptor Agonist, and Serotonin 1d Receptor Agonist. Eletriptan is only found in individuals that have used or taken this drug. Two theories have been proposed to explain the efficacy of 5-HT receptor agonists in a migraine. One theory suggests that activation of 5-HT1 receptors located on intracranial blood vessels, including Read More …

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Avitriptan Drug; Uses, Dosage, Side Effects, Interactions

Avitriptan

Avitriptan drug is an antimigraine drug of the triptan family which was never marketed. It acts as a 5-HT1B and 5-HT1D receptor agonist. Avitriptan should be able to abort migraine headaches in patients, but may exhibit sumatriptan-like effects on coronary arteries. Initial clinical studies have demonstrated the therapeutic action of the drug in acute migraine. Mechanism of Action of Avitriptan Side Effects The most common allergic reactions like skin rash, itching or hives, swelling Read More …

Almotriptan; Uses, Dosage, Side Effects, Interactions

Almotriptan

Almotriptan is a sulfonamide triptan with extracerebral, intracranial vasoconstrictor activity. Almotriptan selectively binds to and activates serotonin 5-HT 1B and 1D receptors in the central nervous system (CNS), thereby causing extracerebral, intracranial blood vessel constriction. This may lead to pain relief from vascular headaches. Almotriptan may also relieve vascular headaches by preventing the release of vasoactive neuropeptides from perivascular trigeminal axons in the dura mater during a Read More …

Hand Injury; Types, Causes, Symptoms, Diagnosis, Treatment

Hand injury

Hand injury is a kind of injury that contains the muscle, bones, nerve, tendon, ligament, cartilage, synovium, bursa and more. The hand is a very complex organ with multiple joints, different types of ligament, tendons, and nerves. Hand disease injuries are common in society and can result from excessive use, degenerative disorders or trauma. Trauma to the finger or the hand is quite common in society. In Read More …

Antimigraine Drugs; Uses/Indications, Side Effects, Interactions

Antimigraine Drugs

Antimigraine drugs are the groups of drug that are used for treatment or prevention of a migraine. A migraine is a primary headache disorder characterized by recurrent headaches that are moderate to severe. Typically, the headaches affect one half of the head, are pulsating in nature, and last from two to 72 hours. Associated symptoms may include nausea, vomiting, and sensitivity to light, sound, or smell. The pain is generally made worse Read More …

Vonoprazan Drug; Uses, Dosage, Side effects, Interactions

Vonoprazan drug

Vonoprazan drug is an antiulcerent drug that is used for the treatment of gastroesophageal reflux (GERD), heartburn, indigestion, gastritis, dyspepsia, etc. The potassium-competitive acid blocker vonoprazan is as effective as proton-pump inhibitors (PPIs) in healing gastric and duodenal ulcers  To determine if it is also as effective as PPIs in reducing the risk for recurrent nonsteroidal anti-inflammatory drug Vonoprazan fumarate is a first-in-class potassium-competitive acid blocker. Read More …

Soraprazan; Uses, Dosage, Side Effects, Interactions

Soraprazan

Soraprazan is a potent and reversible inhibitor of the gastric H+/K+ ATPase proton pump with potassium-competitive acid blocking (P-CAB) activity. Soraprazan binds very specifically, competitively and reversibly to the potassium binding site of the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting the pump’s activity and the parietal cell secretion of H+ ions into the gastric lumen, the final step in gastric acid production. Soraprazan is an antiulcer Read More …

Revaprazan Hydrochloride; Uses, Dosage, Side Effects

Revaprazan Hydrochloride

Revaprazan Hydrochloride is the hydrochloride salt form of a lipophilic, weak base with potassium-competitive acid blocking (P-CAB) activity.It is a drug that reduces gastric acid secretion which is used for the treatment of gastritis. It acts as an acid pump antagonist (potassium-competitive acid blocker). Revaprazan is approved for use in Korea but is not approved in Europe or the United States. Revaprazan concentrates highly in the gastric parietal Read More …

Linaprazan; Uses, Dosage, Side Effects, Drug Interactions

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Linaprazan is a lipophilic, weak base with potassium-competitive acid blocking (P-CAB) activity. Linaprazan concentrates highly in the gastric parietal cell canaliculus and on entering this acidic environment is instantly protonated and binds competitively and reversibly to the potassium binding site of the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting the pump’s activity and the parietal cell secretion of H+ ions into the gastric lumen, the final Read More …

Picoprazole; Mechanism, Uses, Contraindications, Dosage, Side effects

Picoprazole

Picoprazole is a specific inhibitor of H+/K+-ATPase and binds to 100-kDa polypeptides of the enzyme, dose dependently inhibited opening of the Cl– conductance by Cu2+-o-phenanthroline, indicating that or Picoprazole, inhibited the gastric (H+ + K+)-ATPase in a concentration-and time-dependent manner. Half-maximal inhibition of the (H+ + K+)-ATPase activity was obtained at about 2 . 10(-6)M under standard conditions. In addition to the Read More …